SCHEMBL29628772

SCHEMBL29628772

CCCCCCc1ccc2c(c1)Cc1cc(-c3csc(-c4cccs4)c3-c3ccc4c(c3)Cc3cc(CCCCCC)ccc3-4)ccc1-2

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.39
DRD2 P14416 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39
SLC6A4 P31645 1/20 0.39
GPR3 P46089 1/20 0.36
S1PR1 P21453 2/20 0.35
ADORA1 P30542 2/20 0.33
KDR P35968 1/20 0.33
RARB P10826 2/20 0.33
LTA4H P09960 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23923766 0.87 HTR2A (0.40) HTR2ADRD2SLC6A2HTR2CSLC6A4
SCHEMBL31070976 0.78 ADORA1 (0.45) SLC6A2HTR2CSLC6A4ADORA1KDR
SCHEMBL20235831 0.76 ADORA1 (0.37) HTR2ADRD2SLC6A2HTR2CSLC6A4
SCHEMBL8147208 0.75 HSD17B10 (0.49) HTR2ADRD2SLC6A2HTR2CSLC6A4
SCHEMBL4898274 0.75 HTR2A (0.55) HTR2ADRD2SLC6A2HTR2CSLC6A4
SCHEMBL4887234 0.75 HTR2A (0.55) HTR2ADRD2SLC6A2HTR2CSLC6A4
SCHEMBL4895814 0.75 HTR2A (0.55) HTR2ADRD2SLC6A2HTR2CSLC6A4
SCHEMBL4900272 0.75 HTR2A (0.55) HTR2ADRD2SLC6A2HTR2CSLC6A4
SCHEMBL30369240 0.75 HTR2A (0.55) HTR2ADRD2SLC6A2HTR2CSLC6A4
SCHEMBL996765 0.75 S1PR1 (0.44) HTR2ADRD2SLC6A2HTR2CSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108242445-B Array substrate for thin film transistor and display device thereof 乐金显示有限公司 2022-06-24 CN disclosed