Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29628844 | 0.81 | NPC1 (0.54) | LMNAHTTMEN1KMT2ADPP4 | |
| SCHEMBL21494552 | 0.79 | POLB (0.56) | POLBLMNAHTTL3MBTL1MEN1 | |
| Bromide SCHEMBL1930790 | 0.78 | POLB (0.55) | POLBLMNAHTTL3MBTL1MEN1 | |
| SCHEMBL30577232 | 0.76 | POLB (0.54) | POLBLMNAHTTL3MBTL1MEN1 | |
| SCHEMBL21494517 | 0.75 | MEN1 (0.51) | POLBLMNAHTTL3MBTL1MEN1 | |
| SCHEMBL21494512 | 0.73 | POLB (0.56) | POLBLMNAHTTL3MBTL1MEN1 | |
| SCHEMBL21494519 | 0.73 | LMNA (0.57) | POLBLMNAHTTL3MBTL1MEN1 | |
| SCHEMBL23424751 | 0.72 | NPC1 (0.54) | LMNAHTTMEN1KMT2ADPP4 | |
| SCHEMBL21494543 | 0.72 | POLB (0.49) | POLBLMNAHTTL3MBTL1MEN1 | |
| SCHEMBL18179635 | 0.71 | SIGMAR1 (0.42) | LMNAMEN1KMT2ADPP4NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-01-24 | — | — | US | disclosed |
| EP-3781582-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2021-02-24 | — | — | EP | disclosed |
| CN-111989336-A | Metal complexes comprising amidine and indole fused cyclopentadienyl ligands | 阿朗新科荷兰有限公司 | 2020-11-24 | — | — | CN | disclosed |
| WO-2019201838-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2019-10-24 | — | — | WO | disclosed |
| WO-2019203676-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2019-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | C5, C1S, CLIC4 | POLB 4475/4885LMNA 1730/4885HTT 2177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.