Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | BTK | Q06187 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18688119 | 0.86 | ALOX15 (0.54) | ALOX15BTKKMT2AMAOBNFKB1 | |
| SCHEMBL29517779 | 0.85 | ALOX15 (0.55) | ALOX15GRM5PIM1CHEK1NTRK1 | |
| SCHEMBL29628904 | 0.84 | HCAR3 (0.54) | BTKKMT2A | |
| SCHEMBL25598798 | 0.84 | AAK1 (0.53) | ALOX15BTKKMT2AL3MBTL1AAK1 | |
| SCHEMBL29883452 | 0.82 | ALOX15 (0.51) | ALOX15L3MBTL1FAAHGRM5 | |
| SCHEMBL30808765 | 0.82 | BTK (0.52) | BTKKMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL1015186 | 0.81 | KDM1A (0.43) | ALOX15BTKKMT2AL3MBTL1AAK1 | |
| SCHEMBL1015183 | 0.81 | KDM1A (0.43) | ALOX15BTKKMT2AL3MBTL1AAK1 | |
| SCHEMBL1015184 | 0.81 | KDM1A (0.43) | ALOX15BTKKMT2AL3MBTL1AAK1 | |
| SCHEMBL23591998 | 0.79 | ALOX15 (0.74) | ALOX15PIM1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997080-A1 | BCAT MODULATION | Icagen, LLC (US) | 2022-05-18 | — | — | EP | disclosed |