SCHEMBL29628996

SCHEMBL29628996

Clc1ccccc1-c1cccc(-c2ccccc2Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.71
SCN9A Q15858 2/20 0.51
BACE1 P56817 1/20 0.47
TRPA1 O75762 1/20 0.47
JAK2 O60674 1/20 0.46
JAK1 P23458 1/20 0.46
TYK2 P29597 1/20 0.46
JAK3 P52333 1/20 0.46
MAOB P27338 2/20 0.45
LMNA P02545 1/20 0.45
TSHR P16473 1/20 0.45
AR P10275 1/20 0.44
PDK2 Q15119 1/20 0.44
AOC3 Q16853 1/20 0.44
KAT6A Q92794 1/20 0.44
TNKS2 Q9H2K2 1/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9479255 1.00 CYP2A6 (0.71) CYP2A6SCN9ABACE1TRPA1JAK2
SCHEMBL23759509 0.93 CYP2A6 (0.70) CYP2A6SCN9ABACE1TRPA1JAK2
SCHEMBL31379791 0.91 CYP2A6 (0.67) CYP2A6SCN9ABACE1TRPA1JAK2
SCHEMBL30720413 0.91 CYP2A6 (0.67) CYP2A6SCN9ABACE1TRPA1JAK2
SCHEMBL9762462 0.89 CYP2A6 (0.70) CYP2A6SCN9ABACE1TRPA1JAK2
SCHEMBL29464821 0.88 CYP2A6 (0.62) CYP2A6SCN9ABACE1TRPA1MAOB
SCHEMBL1520883 0.88 CYP2A6 (0.62) CYP2A6SCN9ABACE1TRPA1MAOB
SCHEMBL23238098 0.85 CYP2A6 (0.54) CYP2A6SCN9ABACE1TRPA1JAK2
SCHEMBL24315366 0.84 CYP2A6 (0.58) CYP2A6SCN9AMAOBLMNAAR
SCHEMBL4515089 0.84 CYP2A6 (0.58) CYP2A6SCN9ATSHRTNKS2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621045-A Method for synthesizing polyaromatic hydrocarbon from aryl formaldehyde 长沙资材科技有限公司 2022-06-14 CN disclosed