SCHEMBL29629004

SCHEMBL29629004

Cc1ccc(-c2cccc(-c3ccc4ccccc4c3)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
CYP2A6 P11509 1/20 0.58
HSD17B1 P14061 2/20 0.57
HSD17B2 P37059 2/20 0.57
CYP1A2 P05177 2/20 0.56
CYP3A4 P08684 2/20 0.56
CYP2C9 P11712 2/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 2/20 0.56
TSHR P16473 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ESR1 P03372 4/20 0.55
ESR2 Q92731 4/20 0.55
CTRC Q99895 1/20 0.49
CYP11B1 P15538 2/20 0.48
CYP11B2 P19099 2/20 0.48
CYP17A1 P05093 1/20 0.48
CYP19A1 P11511 1/20 0.48
ALOX5 P09917 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5048952 0.94 CYP2A6 (0.65) TDP1CYP2A6HSD17B1HSD17B2CYP1A2
SCHEMBL21225648 0.89 CYP1A2 (0.47) TDP1CYP2A6HSD17B1HSD17B2CYP1A2
SCHEMBL28162089 0.87 CYP2A6 (0.56) TDP1CYP2A6HSD17B1HSD17B2CYP1A2
SCHEMBL23179575 0.87 HSD17B1 (0.65) HSD17B1HSD17B2CYP1A2CYP3A4CYP2C9
SCHEMBL30340802 0.87 HSD17B1 (0.65) HSD17B1HSD17B2CYP1A2CYP3A4CYP2C9
SCHEMBL25464967 0.87 HSD17B1 (0.65) HSD17B1HSD17B2CYP1A2CYP3A4CYP2C9
SCHEMBL18260215 0.87 HSD17B1 (0.71) HSD17B1HSD17B2CYP1A2CYP3A4CYP2C9
SCHEMBL31502316 0.87 HSD17B1 (0.71) HSD17B1HSD17B2CYP1A2CYP3A4CYP2C9
SCHEMBL4546923 0.87 CTRC (0.57) TDP1CYP2A6HSD17B1HSD17B2CYP1A2
SCHEMBL6209672 0.87 HSD17B1 (0.71) HSD17B1HSD17B2CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621045-A Method for synthesizing polyaromatic hydrocarbon from aryl formaldehyde 长沙资材科技有限公司 2022-06-14 CN disclosed