Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.62 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.55 |
| ▸ | CALCR | P30988 | 4/20 | 0.55 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 4/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.52 |
| ▸ | GRPR | P30550 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29629120 | 1.00 | MC4R (0.62) | MC4RC5AR1CALCRCRHR1CRHR2 | |
| SCHEMBL31474321 | 0.86 | MC4R (0.58) | MC4RC5AR1F2OPRD1 | |
| SCHEMBL31670617 | 0.86 | CALCR (0.55) | MC4RC5AR1CALCRCRHR1CRHR2 | |
| SCHEMBL30431281 | 0.85 | F2 (0.59) | MC4RC5AR1CALCRCRHR1CRHR2 | |
| SCHEMBL31474361 | 0.84 | MC4R (0.62) | MC4RC5AR1CALCRF2OPRD1 | |
| SCHEMBL29656078 | 0.83 | C5AR1 (0.59) | MC4RC5AR1CALCRCRHR1CRHR2 | |
| SCHEMBL31603939 | 0.83 | CALCR (0.70) | CALCRCRHR1CRHR2F2 | |
| SCHEMBL30432686 | 0.83 | C5AR1 (0.66) | MC4RC5AR1CALCRNMBRGRPR | |
| SCHEMBL30432185 | 0.83 | CALCR (0.65) | C5AR1CALCRCRHR1CRHR2OPRD1 | |
| SCHEMBL29569971 | 0.82 | OPRD1 (0.63) | CALCRF2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194787-B | Polypeptide for targeted inhibition of Wnt/beta-catenin signal activity and application thereof | 中国医学科学院药物研究所 | 2022-05-17 | — | — | CN | disclosed |