Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.59 |
| ▸ | KDM1A | O60341 | 3/20 | 0.57 |
| ▸ | MC4R | P32245 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | KDM5A | P29375 | 1/20 | 0.56 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.56 |
| ▸ | CALCR | P30988 | 3/20 | 0.55 |
| ▸ | NPY2R | P49146 | 7/20 | 0.55 |
| ▸ | NPY4R | P50391 | 7/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.55 |
| ▸ | NPY1R | P25929 | 5/20 | 0.55 |
| ▸ | APLNR | P35414 | 1/20 | 0.54 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655924 | 0.89 | C5AR1 (0.59) | C5AR1CALCRNPY2RNPY4RNPY5R | |
| SCHEMBL29588650 | 0.88 | MC4R (0.64) | MC4RCALCRNPY2RNPY4RNPY5R | |
| SCHEMBL29860218 | 0.88 | MC4R (0.64) | MC4RCALCRNPY2RNPY4RNPY5R | |
| SCHEMBL30763301 | 0.88 | CALCR (0.70) | MC4RCALCRNPY2RNPY4RNPY5R | |
| SCHEMBL29903323 | 0.87 | APLNR (0.58) | C5AR1CALCRNPY2RNPY4RNPY5R | |
| SCHEMBL30433090 | 0.87 | CALCR (0.64) | C5AR1CALCRNPY2RNPY4RNPY5R | |
| SCHEMBL29707431 | 0.87 | MC4R (0.62) | C5AR1KDM1AMC4RMAOBKDM5A | |
| SCHEMBL29607011 | 0.87 | APLNR (0.58) | C5AR1MC4RCALCRAPLNR | |
| SCHEMBL31307221 | 0.87 | C5AR1 (0.57) | C5AR1CALCRNPY2RNPY4RNPY5R | |
| SCHEMBL31307222 | 0.87 | C5AR1 (0.56) | C5AR1KDM1ACALCRNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2022-05-31 | — | — | US | claimed |
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2022-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11344548-B2 | Analogs of 3,5-dihydroxypentanoate for bone formation | CYP24A1, CYP27B1, CYP2R1 | C5AR1 802/4885KDM1A 3819/4885MC4R 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.