Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800185 | 0.82 | AOC3 (0.40) | AOC3 | |
| SCHEMBL29629260 | 0.78 | NQO2 (0.51) | PTGS1PTGS2AOC3ALDH1A1SMN1; SMN2 | |
| SCHEMBL12197989 | 0.78 | ALOX5 (0.44) | ALOX5PTGS1PTGS2LMNAALDH1A1 | |
| SCHEMBL29016298 | 0.76 | LMNA (0.41) | LMNAALDH1A1CES2CES1TDP1 | |
| SCHEMBL11526523 | 0.76 | LMNA (0.41) | LMNAALDH1A1CES2CES1TDP1 | |
| SCHEMBL28365870 | 0.72 | ALOX5 (0.50) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL6921262 | 0.72 | ALOX5 (0.50) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL4791126 | 0.72 | ALOX5 (0.50) | ALOX5PTGS1PTGS2LMNASMN1; SMN2 | |
| SCHEMBL24554823 | 0.72 | MAPT (0.50) | PTGS1PTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8773918 | 0.69 | MEN1 (0.52) | AOC3ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114426564-B | Chiral ferrocene phosphine-1, 2-diphenyl ethylenediamine ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-09-08 | — | — | CN | disclosed |
| CN-114426564-A | Chiral ferrocenyl phosphine-1, 2-diphenyl ethylene diamine ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2022-05-03 | — | — | CN | disclosed |