Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15046154 | 0.93 | MAPT (0.56) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 | |
| SCHEMBL6130313 | 0.85 | CES2 (0.50) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 | |
| SCHEMBL6130314 | 0.85 | CES2 (0.50) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 | |
| SCHEMBL19024320 | 0.85 | MAPT (0.66) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 | |
| SCHEMBL1972602 | 0.83 | NR4A1 (0.65) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 | |
| SCHEMBL3860961 | 0.83 | NR4A1 (0.65) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 | |
| SCHEMBL2473970 | 0.83 | NR4A1 (0.65) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 | |
| SCHEMBL2271314 | 0.82 | MAPT (0.61) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 | |
| SCHEMBL2271311 | 0.82 | MAPT (0.61) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 | |
| SCHEMBL26364966 | 0.82 | MAPT (0.47) | MAPTCYP1A2CYP2C19TNFRSF1ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114426564-B | Chiral ferrocene phosphine-1, 2-diphenyl ethylenediamine ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2023-09-08 | — | — | CN | disclosed |
| CN-114426564-A | Chiral ferrocenyl phosphine-1, 2-diphenyl ethylene diamine ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2022-05-03 | — | — | CN | disclosed |