Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.65 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
| ▸ | BAD | Q92934 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1972602 | 1.00 | NR4A1 (0.65) | NR4A1NR4A2NR4A3MAPTCES2 | |
| SCHEMBL3860961 | 1.00 | NR4A1 (0.65) | NR4A1NR4A2NR4A3MAPTCES2 | |
| SCHEMBL6497484 | 0.94 | NR4A1 (0.59) | NR4A1NR4A2NR4A3MAPTCES2 | |
| SCHEMBL1842885 | 0.94 | NR4A1 (0.59) | NR4A1NR4A2NR4A3MAPTCES2 | |
| SCHEMBL6497479 | 0.94 | NR4A1 (0.59) | NR4A1NR4A2NR4A3MAPTCES2 | |
| SCHEMBL6130313 | 0.85 | CES2 (0.50) | NR4A1NR4A2NR4A3MAPTCES2 | |
| SCHEMBL6130314 | 0.85 | CES2 (0.50) | NR4A1NR4A2NR4A3MAPTCES2 | |
| SCHEMBL29629277 | 0.83 | MAPT (0.63) | NR4A1NR4A2NR4A3MAPTCES2 | |
| SCHEMBL29119466 | 0.83 | NR4A1 (0.63) | NR4A1NR4A2NR4A3CES2CES1 | |
| SCHEMBL1842528 | 0.82 | NR4A1 (0.54) | NR4A1NR4A2NR4A3MAPTBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229152-B | 2-bit disubstituted indoline-3-ketone compound and asymmetric synthesis method thereof | 中国药科大学 | 2020-06-23 | — | — | CN | claimed |
| US-20230303496-A1 | SELECTIVE ANDROGEN RECEPTOR COVALENT ANTAGONISTS (SARCAs) AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2023-09-28 | — | — | US | disclosed |
| US-20230303496-A1 | SELECTIVE ANDROGEN RECEPTOR COVALENT ANTAGONISTS (SARCAs) AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2023-09-28 | — | — | US | disclosed |
| CN-110229152-B | 2-bit disubstituted indoline-3-ketone compound and asymmetric synthesis method thereof | 中国药科大学 | 2020-06-23 | — | — | CN | disclosed |
| US-10336678-B2 | Compositions and methods for preparing β,γ-unsaturated acids | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180327343-A1 | COMPOSITIONS AND METHODS FOR PREPARING BETA,GAMMA-UNSATURATED ACIDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2018-11-15 | — | — | US | disclosed |
| EP-1411052-B1 | BENZO-FUSED 5-MEMBERED HETROCYCLE COMPOUNDS,PROCESS FOR PREPARATION OF THE SAME, AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2011-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303496-A1 | SELECTIVE ANDROGEN RECEPTOR COVALENT ANTAGONISTS (SARCAs) AND METHODS OF USE THEREOF | AR, BRCA1, PSMA1 | NR4A1 697/4885NR4A2 556/4885NR4A3 466/4885 |
| US-10336678-B2 | Compositions and methods for preparing β,γ-unsaturated acids | ELOVL5, FASN, ACSL5 | NR4A1 1816/4885NR4A2 3036/4885NR4A3 3137/4885 |
| US-20180327343-A1 | COMPOSITIONS AND METHODS FOR PREPARING BETA,GAMMA-UNSATURATED ACIDS | ELOVL5, FASN, ACSL5 | NR4A1 2107/4885NR4A2 3419/4885NR4A3 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.