Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27325562 | 0.69 | KDM4E (0.30) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL7878556 | 0.63 | NUDT1 (0.37) | KDM4EMEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL29629433 | 0.63 | COMT (0.39) | KDM4EALDH1A1LMNAHPGDALOX15 | |
| SCHEMBL3126519 | 0.61 | PRKCI (0.33) | KDM4EALDH1A1HPGDMAPK1PDE3A | |
| SCHEMBL7878810 | 0.58 | CDC7 (0.45) | MAPK1EGFRMAPK14CYP1A2 | |
| SCHEMBL1188205 | 0.57 | CSNK2A2 (0.30) | — | |
| SCHEMBL19998636 | 0.56 | PRKCI (0.34) | KDM4EMEN1ALDH1A1HPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL28275525 | 0.56 | ALDH1A1 (0.42) | KDM4EMEN1ALDH1A1HPGDMAPK1 | |
| SCHEMBL1504317 | 0.56 | IDO1 (0.48) | LMNASMN1; SMN2MAPK14HSD17B10 | |
| SCHEMBL28654223 | 0.56 | NISCH (0.50) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994138-A1 | ESTROGEN-RELATED RECEPTOR ALPHA (ERRalpha) MODULATORS | Lead Pharma Holding B.V. (NL) | 2022-05-11 | — | — | EP | disclosed |