Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118213 | 1.00 | AKR1B1 (0.54) | AKR1B1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL22138547 | 0.78 | AKR1B1 (0.38) | AKR1B1CYP3A4HPGDTSHRALDH1A1 | |
| SCHEMBL10715975 | 0.76 | AKR1B1 (0.61) | AKR1B1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL10873971 | 0.73 | CYP3A4 (0.59) | AKR1B1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL30168074 | 0.70 | AKR1B1 (1.00) | AKR1B1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL22118215 | 0.70 | AKR1B1 (0.33) | AKR1B1CYP3A4HPGDHSP90AA1MAPK1 | |
| SCHEMBL4575982 | 0.70 | AKR1B1 (1.00) | AKR1B1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL29629487 | 0.70 | AKR1B1 (0.33) | AKR1B1CYP3A4HPGDHSP90AA1MAPK1 | |
| SCHEMBL22118203 | 0.69 | AKR1B1 (0.41) | AKR1B1HPGDHSP90AA1MAPK1NR1I2 | |
| SCHEMBL22138545 | 0.67 | HSD17B10 (0.59) | AKR1B1CYP3A4HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12297311-B2 | Biaryl hydroxythiophene group IV transition metal polymerization with chain transfer capability | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-05-13 | — | — | US | disclosed |
| US-12221508-B2 | Biaryl phenoxy group IV transition metal catalysts for olefin polymerization | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-02-11 | — | — | US | disclosed |
| US-20220169756-A1 | BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-06-02 | — | — | US | disclosed |