SCHEMBL4575982

SCHEMBL4575982

Oc1c(Oc2cc(Cl)c(Cl)c(Cl)c2O)cc(Cl)c(Cl)c1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 3/20 1.00
HPGD P15428 9/20 0.56
HSD17B10 Q99714 8/20 0.56
TSHR P16473 7/20 0.56
MAPK1 P28482 3/20 0.56
CASP1 P29466 1/20 0.48
CYP3A4 P08684 6/20 0.44
HSP90AA1 P07900 3/20 0.44
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
LMNA P02545 4/20 0.38
MAPT P10636 4/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
PGR P06401 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
HSPA5 P11021 2/20 0.38
TBXA2R P21731 2/20 0.38
SLC6A2 P23975 2/20 0.38
RECQL P46063 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30168074 1.00 AKR1B1 (1.00) AKR1B1HPGDHSD17B10TSHRMAPK1
SCHEMBL435162 0.82 AKR1B1 (0.68) AKR1B1HPGDHSD17B10TSHRMAPK1
SCHEMBL8506369 0.81 AKR1B1 (0.68) AKR1B1HPGDHSD17B10TSHRMAPK1
SCHEMBL10715975 0.76 AKR1B1 (0.61) AKR1B1HPGDHSD17B10TSHRMAPK1
Pentachlorophenol SCHEMBL10548213 0.73 HSD17B10 (0.78) AKR1B1HPGDHSD17B10TSHRMAPK1
SCHEMBL29364629 0.73 HSD17B10 (1.00) AKR1B1HPGDHSD17B10TSHRMAPK1
SCHEMBL54380 0.73 HSD17B10 (1.00) AKR1B1HPGDHSD17B10TSHRMAPK1
SCHEMBL69390 0.70 HSD17B10 (0.65) AKR1B1HPGDHSD17B10TSHRMAPK1
SCHEMBL8419258 0.70 AKR1B1 (0.53) AKR1B1HPGDHSD17B10TSHRMAPK1
SCHEMBL22118213 0.70 AKR1B1 (0.54) AKR1B1HPGDHSD17B10TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113350202-A Toothpaste using black gold ore as raw material and preparation method thereof 国康育源(大连)健康管理有限公司 2021-09-07 CN claimed
WO-2019233377-A1 NOVEL SELF-ASSEMBLED AMINO ACID SUPRAMOLECULAR POLYMER, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 苏州欧丽特生物医药有限公司 (CN) 2019-12-12 WO claimed
WO-2019233375-A1 SELF-ASSEMBLED AMINO ACID SUPRAMOLECULAR POLYMER, PREPARATION THEREFOR, AND APPLICATION THEREOF 苏州欧丽特生物医药有限公司 (CN) 2019-12-12 WO claimed
CN-120419555-A Formula and preparation method of marine organism-preventing grease block and marine organism-preventing effect monitoring method 中海油信息科技有限公司 2025-08-05 CN disclosed
CN-115737885-A Medical adhesive for rapid release of antimicrobial agents 艾利丹尼森公司 2023-03-07 CN disclosed
CN-105073934-B Antimicrobial adhesives with improved properties 艾利丹尼森公司 2021-12-28 CN disclosed
CN-113350202-A Toothpaste using black gold ore as raw material and preparation method thereof 国康育源(大连)健康管理有限公司 2021-09-07 CN disclosed
CN-105749323-B Antimicrobial adhesives with improved properties 艾利丹尼森公司 2019-12-13 CN disclosed
WO-2017103956-A1 DISINFECTION OR STERILIZATION DEVICE FOR THE ORAL HYGIENE TOOTHBRUSHES GERLONI ALESSANDRO (IT) 2017-06-22 WO disclosed
WO-2008138386-A1 ABSORBENT ARTICLES COMPRISING ACIDIC CELLULOSIC FIBERS AND/OR ACIDIC SUPERABSORBING MATERIAL, AND BENZOIC ACID, HYDROXY BENZOIC ACID AND ESTERS THEREOF SCA HYGIENE PRODUCTS AB (SE) 2008-11-20 WO disclosed
EP-1942735-A2 ANTIMICROBIAL COMPOSITION AND METHOD Dow Global Technologies Inc. (US) 2008-07-16 EP disclosed
WO-2007050700-A2 ANTIMICROBIAL COMPOSITION AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2007-05-03 WO disclosed
EP-1324660-A1 ANTIMICROBIAL POLYALPHAOLEFIN COMPOSITION Duraban Oy (FI) 2003-07-09 EP disclosed
WO-2002030194-A1 ANTIMICROBIAL POLYALPHAOLEFIN COMPOSITION DURABAN OY (FI) 2002-04-18 WO disclosed
US-4181225-A Wet-tissue pack Salva S.A. (CH) 1980-01-01 US disclosed
US-4143762-A Wet-tissue rack SALVE S.A. (CH) 1979-03-13 US disclosed