SCHEMBL29629602

SCHEMBL29629602

CC(C)=CCc1c(O)cc2oc(-c3ccc(O)cc3)cc(=O)c2c1O

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.83
AKT1 P31749 3/20 0.81
PTPN1 P18031 5/20 0.78
PDE4D Q08499 2/20 0.70
PDE5A O76074 1/20 0.70
ESR1 P03372 1/20 0.70
ESR2 Q92731 1/20 0.70
HPGD P15428 1/20 0.67
GABRP O00591 2/20 0.63
GABRD O14764 2/20 0.63
GABRA1 P14867 2/20 0.63
GABRB1 P18505 2/20 0.63
GABRG2 P18507 2/20 0.63
GABRB3 P28472 2/20 0.63
GABRA5 P31644 2/20 0.63
GABRA3 P34903 2/20 0.63
GABRA2 P47869 2/20 0.63
GABRB2 P47870 2/20 0.63
GABRA4 P48169 2/20 0.63
GABRE P78334 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4834777 1.00 ABCG2 (0.83) ABCG2AKT1PTPN1PDE4DPDE5A
SCHEMBL26621014 0.92 ABCG2 (0.81) ABCG2AKT1PTPN1PDE4DPDE5A
SCHEMBL20954091 0.91 ABCG2 (1.00) ABCG2AKT1PTPN1PDE4DPDE5A
SCHEMBL30410935 0.91 ABCG2 (1.00) ABCG2AKT1PTPN1PDE4DPDE5A
SCHEMBL3336171 0.91 ALOX5 (0.77) ABCG2AKT1PTPN1PDE4DPDE5A
SCHEMBL3336163 0.91 ALOX5 (0.77) ABCG2AKT1PTPN1PDE4DPDE5A
SCHEMBL29833892 0.91 ALOX5 (0.77) ABCG2AKT1PTPN1PDE4DPDE5A
SCHEMBL31691719 0.90 AKT1 (1.00) ABCG2AKT1PTPN1PDE4DPDE5A
SCHEMBL4836863 0.90 AKT1 (1.00) ABCG2AKT1PTPN1PDE4DPDE5A
SCHEMBL24075640 0.88 PTPN1 (1.00) ABCG2AKT1PTPN1PDE4DPDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251758-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS Rothstein, Steven (CA) 2023-10-04 EP claimed
WO-2022109736-A1 POLYPEPTIDES FOR USE IN THE SYNTHESIS OF BIOACTIVE PHENOLIC COMPOUNDS ROTHSTEIN STEVEN (CA) 2022-06-02 WO claimed
CN-119454690-A Application of natural compound in preparing medicine for treating or preventing central nervous system disorder and cardiovascular disease 常州大学 2025-02-18 CN disclosed