Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 1.00 |
| ▸ | AKT1 | P31749 | 3/20 | 0.84 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.74 |
| ▸ | PTGES | O14684 | 1/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.60 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.60 |
| ▸ | MGAM | O43451 | 2/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | IDH1 | O75874 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26621019 | 0.94 | PTPN1 (0.88) | PTPN1AKT1ABCG2PTGESALOX5 | |
| SCHEMBL31691719 | 0.91 | AKT1 (1.00) | PTPN1AKT1ABCG2PTGESALOX5 | |
| SCHEMBL4836863 | 0.91 | AKT1 (1.00) | PTPN1AKT1ABCG2PTGESALOX5 | |
| SCHEMBL26621013 | 0.89 | AKT1 (0.84) | PTPN1AKT1ABCG2PTGESALOX5 | |
| SCHEMBL24074909 | 0.89 | PTPN1 (0.80) | PTPN1AKT1ABCG2PTGESALOX5 | |
| SCHEMBL4834777 | 0.88 | ABCG2 (0.83) | PTPN1AKT1ABCG2PTGESALOX5 | |
| SCHEMBL29629602 | 0.88 | ABCG2 (0.83) | PTPN1AKT1ABCG2PTGESALOX5 | |
| SCHEMBL26621014 | 0.87 | ABCG2 (0.81) | PTPN1AKT1ABCG2PTGESALOX5 | |
| SCHEMBL16769856 | 0.86 | PTGES (0.84) | PTPN1AKT1ABCG2PTGESALOX5 | |
| SCHEMBL29359086 | 0.86 | PTGES (0.84) | PTPN1AKT1ABCG2PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2023-04-13 | — | — | US | disclosed |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-09 | — | — | US | disclosed |
| WO-2021237371-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | PTPN1 395/4885AKT1 972/4885ABCG2 1860/4885 |
| US-20210380513-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | PTPN1 395/4885AKT1 972/4885ABCG2 1860/4885 |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | ADH1A, ADH1C, AHR | PTPN1 395/4885AKT1 972/4885ABCG2 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.