Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24485423 | 1.00 | SLC26A4 (0.43) | SLC26A4MEN1KMT2APOLBLMNA | |
| SCHEMBL24484503 | 0.91 | SLC26A4 (0.42) | SLC26A4MEN1KMT2APOLBLMNA | |
| SCHEMBL29630284 | 0.91 | SLC26A4 (0.42) | SLC26A4MEN1KMT2APOLBLMNA | |
| SCHEMBL29630244 | 0.89 | TDP2 (0.44) | POLBLMNAKDM4EHSD17B10TDP1 | |
| SCHEMBL29095783 | 0.89 | TDP2 (0.44) | POLBLMNAKDM4EHSD17B10TDP1 | |
| SCHEMBL24485230 | 0.88 | SLC26A4 (0.40) | SLC26A4MEN1KMT2APOLBLMNA | |
| SCHEMBL24485049 | 0.82 | SLC26A4 (0.51) | SLC26A4MEN1KMT2APOLBLMNA | |
| SCHEMBL29630264 | 0.82 | SLC26A4 (0.51) | SLC26A4MEN1KMT2APOLBLMNA | |
| SCHEMBL24484512 | 0.81 | SLC26A4 (0.48) | SLC26A4MEN1KMT2APOLBLMNA | |
| SCHEMBL29630147 | 0.81 | SLC26A4 (0.48) | SLC26A4MEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |