Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29095861 | 1.00 | MAPT (0.52) | MAPTLMNAPTGS2ALDH1A1KDM4E | |
| SCHEMBL29630234 | 0.86 | MAPT (0.48) | MAPTLMNAPTGS2ALDH1A1KDM4E | |
| SCHEMBL29095787 | 0.86 | MAPT (0.48) | MAPTLMNAPTGS2ALDH1A1KDM4E | |
| SCHEMBL29095764 | 0.85 | MAPT (0.52) | MAPTLMNAPTGS2ALDH1A1KDM4E | |
| SCHEMBL29630185 | 0.85 | MAPT (0.52) | MAPTLMNAPTGS2ALDH1A1KDM4E | |
| SCHEMBL24484859 | 0.83 | MAPT (0.63) | MAPTLMNAPTGS2ALDH1A1KDM4E | |
| SCHEMBL29629694 | 0.80 | SLC26A4 (0.71) | MAPTLMNAL3MBTL1SLC26A4TSHR | |
| SCHEMBL24484972 | 0.80 | SLC26A4 (0.71) | MAPTLMNAL3MBTL1SLC26A4TSHR | |
| SCHEMBL29095822 | 0.78 | PTGS2 (0.67) | MAPTLMNAPTGS2ALDH1A1KDM4E | |
| SCHEMBL24485030 | 0.78 | PTGS2 (0.66) | MAPTLMNAPTGS2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |