SCHEMBL29630381

SCHEMBL29630381

NC(=O)CC[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CCC(N)=O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 1/20 0.49
FOLH1 Q04609 3/20 0.47
RIMKLA Q8IXN7 1/20 0.47
NAALAD2 Q9Y3Q0 1/20 0.47
GNPAT O15228 1/20 0.47
ALOX15 P16050 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
KMT2A Q03164 1/20 0.46
DPP4 P27487 2/20 0.46
DPP8 Q6V1X1 2/20 0.46
DPP9 Q86TI2 2/20 0.46
BACE1 P56817 6/20 0.45
GRM8 O00222 1/20 0.43
GRM6 O15303 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GSR P00390 1/20 0.43
CYP1A2 P05177 1/20 0.43
GRIK1 P39086 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31299998 1.00 BMP1 (0.49) BMP1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL30288867 0.96 FOLH1 (0.51) BMP1FOLH1RIMKLANAALAD2ALOX15
SCHEMBL29706692 0.96 FOLH1 (0.51) BMP1FOLH1RIMKLANAALAD2ALOX15
SCHEMBL30596280 0.96 FOLH1 (0.51) BMP1FOLH1RIMKLANAALAD2ALOX15
SCHEMBL29636521 0.96 FOLH1 (0.51) BMP1FOLH1RIMKLANAALAD2ALOX15
SCHEMBL31410858 0.94 BACE1 (0.48) BMP1FOLH1RIMKLANAALAD2ALOX15
SCHEMBL31448323 0.94 FOLH1 (0.53) BMP1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL30607422 0.94 FOLH1 (0.53) BMP1FOLH1RIMKLANAALAD2GNPAT
SCHEMBL31514361 0.93 ALOX15 (0.50) BMP1GNPATALOX15BLMPMP22
SCHEMBL4726036 0.93 FOLH1 (0.55) BMP1FOLH1RIMKLANAALAD2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 US disclosed