Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.45 |
| ▸ | NRP1 | O14786 | 2/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490593 | 0.89 | OPRK1 (0.45) | EPHA2NRP1NTSR2NTSR1OPRM1 | |
| SCHEMBL30658582 | 0.88 | XIAP (0.45) | XIAPEPHA2GRB2OPRM1OPRK1 | |
| SCHEMBL30487567 | 0.87 | NTSR2 (0.47) | NTSR2NTSR1SORT1OPRM1OPRK1 | |
| SCHEMBL29379382 | 0.87 | NTSR2 (0.48) | NRP1NTSR2NTSR1PLK1SORT1 | |
| SCHEMBL30361589 | 0.86 | NTSR2 (0.52) | XIAPNTSR2NTSR1SORT1 | |
| SCHEMBL31657757 | 0.86 | NMUR2 (0.48) | EPHA2 | |
| SCHEMBL29886811 | 0.86 | EPHA2 (0.45) | XIAPEPHA2NRP1GRB2NTSR2 | |
| SCHEMBL30676238 | 0.86 | EPHA2 (0.46) | XIAPEPHA2GRB2NTSR2NTSR1 | |
| SCHEMBL29801896 | 0.86 | NRP1 (0.42) | EPHA2NRP1GRB2OPRM1OPRK1 | |
| SCHEMBL22872708 | 0.86 | NRP1 (0.54) | EPHA2NRP1GRB2NTSR2NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807899-B2 | Biochemical reaction methods and reagents comprising intrinsically disordered regions | Biocrucible Limited | 2023-11-07 | — | — | US | disclosed |
| US-20220145378-A1 | BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS | Biocrucible Limited (GB) | 2022-05-12 | — | — | US | disclosed |