SCHEMBL29630573

SCHEMBL29630573

NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 5/20 0.56
NPY1R P25929 4/20 0.56
NPY2R P49146 3/20 0.56
ERAP2 Q6P179 1/20 0.50
LNPEP Q9UIQ6 1/20 0.50
NPY5R Q15761 2/20 0.49
ENPEP Q07075 3/20 0.48
UTS2R Q9UKP6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389091 0.92 MMP2 (0.51) NPY4RNPY1RNPY2RERAP2LNPEP
SCHEMBL30512526 0.91 BACE1 (0.51) NPY4RNPY1RNPY2RENPEP
SCHEMBL5032917 0.91 ENPEP (0.56) NPY4RNPY1RNPY2RERAP2LNPEP
SCHEMBL29697056 0.90 ENPEP (0.53) NPY4RNPY1RNPY2RENPEP
SCHEMBL30149609 0.90 ENPEP (0.53) NPY4RNPY1RNPY2RENPEP
SCHEMBL29591071 0.90 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5R
SCHEMBL31018320 0.90 NPY4R (0.54) NPY4RNPY1RNPY2RERAP2LNPEP
SCHEMBL4420809 0.90 ENPEP (0.56) NPY4RNPY1RNPY2RERAP2LNPEP
SCHEMBL30799753 0.89 NPY4R (0.66) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29985813 0.89 NPY4R (0.56) NPY4RNPY1RNPY2RERAP2LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 US disclosed