Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.50 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630452 | 0.94 | FOLH1 (0.56) | BACE1FOLH1CTSDBACE2DPP4 | |
| SCHEMBL29590577 | 0.94 | FOLH1 (0.56) | BACE1FOLH1CTSDBACE2DPP4 | |
| SCHEMBL29591568 | 0.93 | TASP1 (0.52) | BACE1TASP1FOLH1CTSDMME | |
| SCHEMBL30473801 | 0.93 | FOLH1 (0.57) | BACE1FOLH1CTSDBACE2DPP4 | |
| SCHEMBL29377291 | 0.89 | BACE1 (0.51) | BACE1CTSDDPP4DPP8DPP9 | |
| SCHEMBL29679534 | 0.89 | FOLH1 (0.56) | BACE1FOLH1CTSDBACE2 | |
| SCHEMBL29649110 | 0.89 | MME (0.49) | BACE1TASP1FOLH1CTSDMME | |
| SCHEMBL29381184 | 0.89 | DPP4 (0.50) | BACE1TASP1FOLH1CTSDMME | |
| SCHEMBL30480113 | 0.89 | FOLH1 (0.61) | BACE1FOLH1CTSDBACE2DPP4 | |
| SCHEMBL30060796 | 0.89 | DPP4 (0.52) | BACE1FOLH1CTSDBACE2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807899-B2 | Biochemical reaction methods and reagents comprising intrinsically disordered regions | Biocrucible Limited | 2023-11-07 | — | — | US | disclosed |
| US-20220145378-A1 | BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS | Biocrucible Limited (GB) | 2022-05-12 | — | — | US | disclosed |