Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.59 |
| ▸ | MME | P08473 | 9/20 | 0.59 |
| ▸ | CPA1 | P15085 | 6/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25626025 | 0.92 | ACE (0.60) | ACEMMECPA1ACE2ANPEP | |
| SCHEMBL30416809 | 0.86 | ACE (0.53) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL30051541 | 0.86 | ACE (0.64) | ACEMMECPA1ACE2 | |
| SCHEMBL29644411 | 0.85 | MME (0.52) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL25626030 | 0.84 | ACE (0.63) | ACEMMECPA1ACE2 | |
| SCHEMBL25626301 | 0.84 | ACE (0.63) | ACEMMECPA1ACE2 | |
| SCHEMBL29472195 | 0.84 | F2 (0.52) | NTSR2NTSR1 | |
| SCHEMBL30139031 | 0.84 | ACE (0.56) | ACEMMECPA1ACE2ANPEP | |
| SCHEMBL30895730 | 0.84 | ACE (0.65) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL15692291 | 0.84 | ACE (0.65) | ACEMMECPA1ACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807899-B2 | Biochemical reaction methods and reagents comprising intrinsically disordered regions | Biocrucible Limited | 2023-11-07 | — | — | US | disclosed |
| US-20220145378-A1 | BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS | Biocrucible Limited (GB) | 2022-05-12 | — | — | US | disclosed |