Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.52 |
| ▸ | ACE | P12821 | 5/20 | 0.51 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.48 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367266 | 0.96 | ENPEP (0.52) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL29822475 | 0.95 | MME (0.56) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL13588078 | 0.91 | MME (0.63) | MMEACECHRNA1CHRNGCHRNB1 | |
| SCHEMBL29602654 | 0.91 | MME (0.63) | MMEACECHRNA1CHRNGCHRNB1 | |
| SCHEMBL29350849 | 0.91 | MME (0.63) | MMEACECHRNA1CHRNGCHRNB1 | |
| SCHEMBL29603463 | 0.91 | MME (0.63) | MMEACECHRNA1CHRNGCHRNB1 | |
| SCHEMBL30416809 | 0.90 | ACE (0.53) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL4257186 | 0.89 | OPRD1 (0.50) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL4257177 | 0.89 | OPRD1 (0.50) | MMEACECPA1ACE2FOLH1 | |
| SCHEMBL479126 | 0.89 | ACE (0.60) | MMEACECPA1ACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220289846-A1 | ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 | ZYDUS LIFESCIENCES LIMITED (IN) | 2022-09-15 | — | — | US | claimed |
| US-12516121-B2 | Antibodies to human programmed death receptor PD-1 | ZYDUS LIFESCIENCES LIMITED (IN) | 2026-01-06 | — | — | US | disclosed |
| US-20220289846-A1 | ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 | ZYDUS LIFESCIENCES LIMITED (IN) | 2022-09-15 | — | — | US | disclosed |
| EP-3997126-A1 | ANTIBODIES TO HUMAN PROGRAMMED DEATH RECEPTOR PD-1 | Cadila Healthcare Limited (IN) | 2022-05-18 | — | — | EP | disclosed |