Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 13/20 | 0.50 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29590401 | 0.94 | BACE1 (0.51) | OPRM1OPRD1OPRK1BACE1BACE2 | |
| SCHEMBL10601764 | 0.93 | OPRD1 (0.52) | OPRM1OPRD1OPRK1NAALAD2 | |
| SCHEMBL30987807 | 0.91 | BACE1 (0.53) | OPRM1OPRD1OPRK1BACE1BACE2 | |
| SCHEMBL30193015 | 0.91 | BACE1 (0.53) | OPRM1OPRD1OPRK1BACE1BACE2 | |
| SCHEMBL31134839 | 0.90 | BACE1 (0.57) | BACE1BACE2NAALAD2CTSD | |
| SCHEMBL29470277 | 0.90 | BACE1 (0.55) | OPRM1OPRD1OPRK1BACE1BACE2 | |
| SCHEMBL30880911 | 0.89 | NAALAD2 (0.57) | OPRM1OPRD1OPRK1BACE1BACE2 | |
| SCHEMBL29455241 | 0.89 | OPRD1 (0.55) | OPRM1OPRD1OPRK1 | |
| SCHEMBL3772408 | 0.89 | NAALAD2 (0.59) | OPRM1OPRD1OPRK1NAALAD2 | |
| SCHEMBL29349961 | 0.89 | NAALAD2 (0.59) | OPRM1OPRD1OPRK1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807899-B2 | Biochemical reaction methods and reagents comprising intrinsically disordered regions | Biocrucible Limited | 2023-11-07 | — | — | US | disclosed |
| US-20220145378-A1 | BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS | Biocrucible Limited (GB) | 2022-05-12 | — | — | US | disclosed |