SCHEMBL29630837

SCHEMBL29630837

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nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 3/20 0.57
BACE1 P56817 6/20 0.45
CTSD P07339 2/20 0.45
NOD1 Q9Y239 1/20 0.42
ENPEP Q07075 5/20 0.41
PDCD1LG2 Q9BQ51 1/20 0.41
CD274 Q9NZQ7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30044195 1.00 ECE1 (0.57) ECE1BACE1CTSDNOD1ENPEP
SCHEMBL29630811 1.00 ECE1 (0.57) ECE1BACE1CTSDNOD1ENPEP
SCHEMBL29630557 1.00 ECE1 (0.57) ECE1BACE1CTSDNOD1ENPEP
SCHEMBL30122820 1.00 ECE1 (0.57) ECE1BACE1CTSDNOD1ENPEP
SCHEMBL29630762 1.00 ECE1 (0.57) ECE1BACE1CTSDNOD1ENPEP
SCHEMBL30122887 0.97 ECE1 (0.55) ECE1BACE1CTSDENPEPPDCD1LG2
SCHEMBL11517272 0.90 ECE1 (0.63) ECE1NOD1PDCD1LG2CD274
SCHEMBL30910815 0.90 ECE1 (0.63) ECE1NOD1PDCD1LG2CD274
SCHEMBL21473104 0.90 ECE1 (0.63) ECE1NOD1PDCD1LG2CD274
SCHEMBL2490629 0.90 ECE1 (0.63) ECE1NOD1PDCD1LG2CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230414771-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY CONJUGATED COMPLEXES FOR TARGETED DELIVERY AND ACTIVATION YAFEI SHANGHAI BIOLOGY MEDICINE SCIENCE & TECHNOLOGY CO., LTD. (CN) 2023-12-28 US claimed
EP-4108675-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY COUPLING COMPLEX WHICH IS DELIVERED AND ACTIVATED IN TARGETED MANNER Yafei Shanghai Biolog Medicine Science & Technology Co., Ltd. (CN) 2022-12-28 EP claimed
US-11319341-B2 Immune-stimulating soluble doxorubicin-conjugated complex YAFEI (SHANGHAI) BIOPHARMACEUTICAL CO., LTD. (CN) 2022-05-03 US claimed
CN-113274507-B Preparation and use of targeted delivery and activation immunostimulatory conjugate complexes 亚飞(上海)生物医药科技有限公司 2025-02-28 CN disclosed
US-20230414771-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY CONJUGATED COMPLEXES FOR TARGETED DELIVERY AND ACTIVATION YAFEI SHANGHAI BIOLOGY MEDICINE SCIENCE & TECHNOLOGY CO., LTD. (CN) 2023-12-28 US disclosed
EP-4108675-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY COUPLING COMPLEX WHICH IS DELIVERED AND ACTIVATED IN TARGETED MANNER Yafei Shanghai Biolog Medicine Science & Technology Co., Ltd. (CN) 2022-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319341-B2 Immune-stimulating soluble doxorubicin-conjugated complex TLR3, CD40, TLR6 ECE1 1561/4885BACE1 2608/4885CTSD 1154/4885
US-20230414771-A1 PREPARATION AND USE OF IMMUNOSTIMULATORY CONJUGATED COMPLEXES FOR TARGETED DELIVERY AND ACTIVATION CD74, PAICS, MIF ECE1 3284/4885BACE1 3856/4885CTSD 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.