Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | DHPS | P49366 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2048285 | 1.00 | HDAC1 (0.52) | HDAC1HDAC4HDAC6ATMDRD2 | |
| SCHEMBL2025017 | 0.83 | KMT2A (0.55) | HDAC1DRD2DRD3ACHEMEN1 | |
| SCHEMBL2023743 | 0.82 | HDAC1 (0.55) | HDAC1HDAC4HDAC6ACHEMEN1 | |
| SCHEMBL2019162 | 0.80 | HDAC1 (0.56) | HDAC1HDAC4HDAC6ACHEMEN1 | |
| SCHEMBL15120603 | 0.79 | HDAC1 (0.55) | HDAC1HDAC4HDAC6ACHEMEN1 | |
| SCHEMBL31391661 | 0.79 | KDM4E (0.55) | HDAC1HDAC4HDAC6ACHEMEN1 | |
| SCHEMBL16850291 | 0.79 | HDAC1 (0.58) | HDAC1HDAC4HDAC6ACHEMEN1 | |
| SCHEMBL20028546 | 0.79 | HDAC1 (0.58) | HDAC1HDAC4HDAC6ACHEMEN1 | |
| SCHEMBL29010959 | 0.79 | KDM4E (0.55) | HDAC1HDAC4HDAC6ACHEMEN1 | |
| SCHEMBL27137063 | 0.78 | DRD3 (0.46) | HDAC1HDAC4HDAC6DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507177-B | Method for preparing functionalized 2- (3-oxo-isoindoline-1-subunit) methyl acetate from carbon dioxide | 常州大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-114507177-A | Method for preparing functionalized 2- (3-oxoisoindoline-1-subunit) methyl acetate from carbon dioxide | 常州大学 | 2022-05-17 | — | — | CN | disclosed |