Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 13/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853696 | 1.00 | HRH3 (0.53) | HRH3AOC3AKR1C3RORCME2 | |
| SCHEMBL5233548 | 0.84 | AOC3 (0.51) | HRH3AOC3AKR1C3RORC | |
| SCHEMBL5230760 | 0.83 | RORC (0.49) | HRH3AOC3RORC | |
| SCHEMBL4321560 | 0.81 | AOC3 (0.59) | HRH3AOC3RORC | |
| SCHEMBL29631009 | 0.81 | AOC3 (0.51) | HRH3AOC3RORC | |
| SCHEMBL3853508 | 0.80 | HRH3 (0.57) | HRH3 | |
| SCHEMBL30564998 | 0.80 | HRH3 (0.57) | HRH3 | |
| SCHEMBL30922297 | 0.80 | CHKA (0.51) | HRH3 | |
| SCHEMBL31073166 | 0.78 | HRH3 (0.44) | HRH3AOC3 | |
| SCHEMBL1115477 | 0.78 | AKR1C3 (0.68) | AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111636-A1 | FUSED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |