Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 13/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630875 | 1.00 | HRH3 (0.53) | HRH3AOC3AKR1C3RORCME2 | |
| SCHEMBL5233548 | 0.84 | AOC3 (0.51) | HRH3AOC3AKR1C3RORC | |
| SCHEMBL5230760 | 0.83 | RORC (0.49) | HRH3AOC3RORC | |
| SCHEMBL4321560 | 0.81 | AOC3 (0.59) | HRH3AOC3RORC | |
| SCHEMBL29631009 | 0.81 | AOC3 (0.51) | HRH3AOC3RORC | |
| SCHEMBL3853508 | 0.80 | HRH3 (0.57) | HRH3 | |
| SCHEMBL30564998 | 0.80 | HRH3 (0.57) | HRH3 | |
| SCHEMBL30922297 | 0.80 | CHKA (0.51) | HRH3 | |
| SCHEMBL31073166 | 0.78 | HRH3 (0.44) | HRH3AOC3 | |
| SCHEMBL1115477 | 0.78 | AKR1C3 (0.68) | AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572811-B2 | Immunosuppressant compounds and compositions | IRM LLC (BM) | 2009-08-11 | — | — | US | disclosed |
| US-20070203100-A1 | Immunosuppressant Compounds and Compositions | IRM LLC (BM) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203100-A1 | Immunosuppressant Compounds and Compositions | ICOS, EDNRA, NFATC1 | HRH3 1062/4885AOC3 4766/4885AKR1C3 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.