Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18016239 | 1.00 | ADRB2 (0.38) | ADRB2CHRM3ACHEMAOAMAOB | |
| SCHEMBL17978750 | 0.93 | ADRB2 (0.40) | ADRB2CHRM3ACHEMAOAMAOB | |
| SCHEMBL17985970 | 0.84 | ADRB2 (0.43) | ADRB2CHRM3ACHEMAOAMAOB | |
| SCHEMBL17985969 | 0.84 | ADRB2 (0.43) | ADRB2CHRM3ACHEMAOAMAOB | |
| SCHEMBL15772032 | 0.83 | ADRB2 (0.34) | ADRB2 | |
| SCHEMBL15772034 | 0.83 | ADRB2 (0.34) | ADRB2 | |
| SCHEMBL17978841 | 0.82 | HDAC3 (0.40) | ADRB2 | |
| SCHEMBL18016237 | 0.82 | ADRB2 (0.36) | ADRB2 | |
| SCHEMBL18269503 | 0.82 | L3MBTL1 (0.34) | ADRB2 | |
| SCHEMBL17979063 | 0.82 | HDAC3 (0.40) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256464-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2022-05-11 | — | — | EP | disclosed |