Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27945037 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CASP1CASP7RAB9A | |
| SCHEMBL30736438 | 0.82 | ALDH1A1 (0.77) | ALDH1A1HSD17B10CASP1CASP7RAB9A | |
| SCHEMBL23293661 | 0.79 | ALDH1A1 (0.75) | ALDH1A1HSD17B10CASP1CASP7RAB9A | |
| SCHEMBL2173458 | 0.78 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CASP1CASP7RAB9A | |
| SCHEMBL6362296 | 0.77 | CASR (0.50) | ALDH1A1HSD17B10RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL27190050 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HSD17B10CASP1CASP7RAB9A | |
| SCHEMBL27945041 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CASP1CASP7RAB9A | |
| SCHEMBL21165547 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CASP1CASP7RAB9A | |
| SCHEMBL10075563 | 0.74 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CASP1CASP7RAB9A | |
| SCHEMBL21093204 | 0.74 | RAB9A (0.60) | ALDH1A1HSD17B10CASP1CASP7RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195471-B | Polysubstituted pyridone derivative and application thereof in medicine | 苏州浦合医药科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110520416-B | Polysubstituted pyridone derivative, preparation method and medical application thereof | 北京越之康泰生物医药科技有限公司 | 2022-06-03 | — | — | CN | disclosed |