Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.59 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | MERTK | Q12866 | 1/20 | 0.53 |
| ▸ | JAK2 | O60674 | 5/20 | 0.53 |
| ▸ | JAK1 | P23458 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
| ▸ | GRK2 | P25098 | 4/20 | 0.52 |
| ▸ | GRK5 | P34947 | 4/20 | 0.52 |
| ▸ | FLT3 | P36888 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | MST1R | Q04912 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21776583 | 1.00 | MET (0.59) | METAXLMERTKJAK2JAK1 | |
| SCHEMBL28343404 | 0.88 | MET (0.59) | METAXLMERTKJAK2JAK1 | |
| SCHEMBL24304281 | 0.87 | MET (0.46) | METAXLMERTKJAK2JAK1 | |
| SCHEMBL30387845 | 0.87 | MET (0.61) | METAXLMERTKGRK2GRK5 | |
| SCHEMBL21776610 | 0.87 | MET (0.61) | METAXLMERTKGRK2GRK5 | |
| SCHEMBL29631682 | 0.86 | MET (0.64) | METAXLMERTKJAK2JAK1 | |
| SCHEMBL28346361 | 0.86 | MET (0.64) | METAXLMERTKJAK2JAK1 | |
| SCHEMBL29631680 | 0.85 | MET (0.59) | METAXLMERTKJAK2JAK1 | |
| SCHEMBL28343405 | 0.85 | MET (0.59) | METAXLMERTKJAK2JAK1 | |
| SCHEMBL30388140 | 0.83 | MET (0.51) | METFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195471-B | Polysubstituted pyridone derivative and application thereof in medicine | 苏州浦合医药科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110520416-B | Polysubstituted pyridone derivative, preparation method and medical application thereof | 北京越之康泰生物医药科技有限公司 | 2022-06-03 | — | — | CN | disclosed |