Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2043001 | 0.91 | MAPT (0.53) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Acetic Acid SCHEMBL7113664 | 0.91 | MAPT (0.53) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Acetic Acid SCHEMBL8968769 | 0.91 | MAPT (0.53) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Benzidine SCHEMBL28008038 | 0.91 | TDP1 (0.50) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Benzidine SCHEMBL28860193 | 0.86 | ALDH1A1 (0.65) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Benzidine SCHEMBL2466323 | 0.85 | ALDH1A1 (0.85) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Acetic Acid SCHEMBL2473166 | 0.85 | SMN1; SMN2 (0.57) | HSD17B10MAPTSMN1; SMN2TSHRHTT | |
| Benzidine SCHEMBL9980982 | 0.85 | ALDH1A1 (0.85) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Benzidine SCHEMBL29383364 | 0.84 | TDP1 (0.55) | TDP1CYP3A4ALDH1A1TP53HSD17B10 | |
| Benzidine SCHEMBL28690244 | 0.84 | TDP1 (0.55) | TDP1CYP3A4ALDH1A1TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109724976-B | Tree male and female identification method based on paper chromatography | 塔里木大学 | 2021-05-14 | — | — | CN | claimed |
| CN-109724977-B | Simple and convenient tree male and female identification method | 塔里木大学 | 2021-05-14 | — | — | CN | claimed |
| CN-109724977-A | A kind of trees Sex judging method of simplicity | 塔里木大学 | 2019-05-07 | — | — | CN | claimed |
| CN-109724976-A | Trees Sex judging method based on paper chromatography | 塔里木大学 | 2019-05-07 | — | — | CN | claimed |
| CN-107242071-A | A kind of implantation methods for lifting yellow peach commodity fruit rate | 马鞍山市绿营林业有限公司 | 2017-10-13 | — | — | CN | claimed |
| CN-119212567-A | Method for preparing cereal tempeh, cereal tempeh prepared by said method, sauce comprising prepared cereal tempeh, and preparation method thereof | CJ第一制糖株式会社 | 2024-12-27 | — | — | CN | disclosed |
| CN-119156141-A | Preparation method of tempeh, tempeh prepared from tempeh, sauce containing tempeh and preparation method of sauce | CJ第一制糖株式会社 | 2024-12-17 | — | — | CN | disclosed |
| CN-109724976-B | Tree male and female identification method based on paper chromatography | 塔里木大学 | 2021-05-14 | — | — | CN | disclosed |
| CN-109724977-B | Simple and convenient tree male and female identification method | 塔里木大学 | 2021-05-14 | — | — | CN | disclosed |
| CN-112362435-A | Cell staining reagent and cell staining method | 深圳安侣医学科技有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-109724976-A | Trees Sex judging method based on paper chromatography | 塔里木大学 | 2019-05-07 | — | — | CN | disclosed |
| CN-109724977-A | A kind of trees Sex judging method of simplicity | 塔里木大学 | 2019-05-07 | — | — | CN | disclosed |
| CN-106718846-A | A kind of breeding method of orchid | 山西大学 | 2017-05-31 | — | — | CN | disclosed |
| CN-103302307-B | Preparation method of silver nano particles and method for facilitating germination of cucumber seeds and growth and development of seedlings with silver nano particles | UNIV TONGHUA NORMAL | 2015-04-08 | — | — | CN | disclosed |
| CN-103302307-A | Preparation method of silver nano particles and method for facilitating germination of cucumber seeds and growth and development of seedlings with silver nano particles | UNIV TONGHUA NORMAL | 2013-09-18 | — | — | CN | disclosed |
| CN-102499071-A | Chemical mutation breeding method for bougainvillea | SHENZHEN XIANHU BOTAN GARDEN ADMINISTRATION | 2012-06-20 | — | — | CN | disclosed |
| US-7770534-B2 | Changed condition indicator | THERMOPROX | 2010-08-10 | — | — | US | disclosed |
| US-20070151502-A1 | Changed condition indicator | THERMOPROX | 2007-07-05 | — | — | US | disclosed |
| US-5231034-A | Coloring solutions by reaction with cupric chloride, centrifuging to obtain a pellet and supernatant, detection | MCLEAN HOSPITAL (US) | 1993-07-27 | — | — | US | disclosed |
| CN-1070947-A | Detect the watermelon and muskmelon seed purity with isozyme | DAQING NORMAL SPECIAL SCHOOL (CN) | 1993-04-14 | — | — | CN | disclosed |