Benzidine

Benzidine

SCHEMBL9980982

Nc1ccc(-c2ccc(N)cc2)cc1.Nc1ccc(-c2ccc(N)cc2)cc1.OO

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.85
CYP3A4 P08684 4/20 0.85
TDP1 Q9NUW8 2/20 0.85
TP53 P04637 2/20 0.85
HSD17B10 Q99714 4/20 0.75
TAAR1 Q96RJ0 2/20 0.75
MAPT P10636 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
CA14 Q9ULX7 3/20 0.53
ALOX15 P16050 3/20 0.53
CA3 P07451 1/20 0.53
THRB P10828 1/20 0.53
CA6 P23280 1/20 0.53
CASP1 P29466 1/20 0.53
HIF1A Q16665 1/20 0.53
KIF11 P52732 1/20 0.52
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
KDM4E B2RXH2 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL2466323 1.00 ALDH1A1 (0.85) ALDH1A1CYP3A4TDP1TP53HSD17B10
Benzidine SCHEMBL27593681 0.92 CYP3A4 (0.87) ALDH1A1CYP3A4TDP1TP53HSD17B10
Benzidine SCHEMBL29120747 0.92 ALDH1A1 (0.85) ALDH1A1CYP3A4TDP1TP53HSD17B10
SCHEMBL28842081 0.92 CYP3A4 (1.00) ALDH1A1CYP3A4TDP1TP53HSD17B10
SCHEMBL2024128 0.92 CYP3A4 (1.00) ALDH1A1CYP3A4TDP1TP53HSD17B10
Benzidine SCHEMBL720393 0.92 CYP3A4 (1.00) ALDH1A1CYP3A4TDP1TP53HSD17B10
Benzidine SCHEMBL5140469 0.92 CYP3A4 (1.00) ALDH1A1CYP3A4TDP1TP53HSD17B10
Benzidine SCHEMBL29021 0.92 CYP3A4 (1.00) ALDH1A1CYP3A4TDP1TP53HSD17B10
SCHEMBL258287 0.92 CYP3A4 (1.00) ALDH1A1CYP3A4TDP1TP53HSD17B10
Benzidine SCHEMBL28390882 0.89 CYP3A4 (0.81) ALDH1A1CYP3A4TDP1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114667922-B Bougainvillea spectabilis crossbreeding method and application 云南为君开园林工程有限公司(CN) 2023-01-13 CN claimed
CN-114667922-A Bougainvillea spectabilis crossbreeding method and application 云南为君开园林工程有限公司 2022-06-28 CN claimed
CN-105850714-B Dendrobium candidum breeding method and corresponding preparation method based on development of floral organs 浙江大学 2018-04-24 CN claimed
CN-107782725-A A kind of pseudo-ginseng stigma vigour assay method 文山苗乡三七科技有限公司 2018-03-09 CN claimed
CN-105850714-A Dendrobium officinale seed preparation method based on development of flower organs and corresponding obtaining method 浙江大学 2016-08-17 CN claimed
CN-100563430-C The method of inducing poplar plant embryo sac chromosome doubling to select and breed triploid UNIV BEIJING FORESTRY (CN) 2009-12-02 CN claimed
CN-101147465-A Method for inducing plant embryo sac chromosome doubling to select and breed triploid UNIV BEIJING FORESTRY (CN) 2008-03-26 CN claimed
CN-116439122-B Method for obtaining distant hybridization offspring between butterfly orchid and cymbidium multiflorum 中国农业科学院蔬菜花卉研究所 2024-03-26 CN disclosed
CN-111939263-B Pharmaceutical composition, traditional Chinese medicine composition, extract thereof, preparation, medicament and application 上海海聚生物科技有限公司 2023-09-12 CN disclosed
CN-116439122-A Method for producing hybrid seeds of phalaenopsis and cymbidium floribundum by distant hybridization 中国农业科学院蔬菜花卉研究所 2023-07-18 CN disclosed
CN-116420525-A Composition and method for improving stamina and fruit setting rate of mango flowers under low-temperature stress condition 中国热带农业科学院南亚热带作物研究所 2023-07-14 CN disclosed
CN-115005094-B Composition for improving artificial hybridization fertilization success rate of rhizoma polygonati, improving method and application 贵州师范大学 2023-04-25 CN disclosed
CN-114667922-B Bougainvillea spectabilis crossbreeding method and application 云南为君开园林工程有限公司(CN) 2023-01-13 CN disclosed
CN-100563430-C The method of inducing poplar plant embryo sac chromosome doubling to select and breed triploid UNIV BEIJING FORESTRY (CN) 2009-12-02 CN disclosed
CN-101147465-A Method for inducing plant embryo sac chromosome doubling to select and breed triploid UNIV BEIJING FORESTRY (CN) 2008-03-26 CN disclosed
EP-0207936-A4 ENZYME IMMUNOASSAY WITH TWO-PART SOLUTION OF TETRAMETHYLBENZIDINE AS CHROMOGEN. HYGEIA SCIENCES LTD (US) 1989-04-24 EP disclosed
EP-0207936-A1 ENZYME IMMUNOASSAY WITH TWO-PART SOLUTION OF TETRAMETHYLBENZIDINE AS CHROMOGEN HYGEIA SCIENCES LIMITED PARTNERSHIP (US) 1987-01-14 EP disclosed
WO-1986004421-A1 ENZYME IMMUNOASSAY WITH TWO-PART SOLUTION OF TETRAMETHYLBENZIDINE AS CHROMOGEN HYGEIA SCIENCES LIMITED PARTNERSHIP (US) 1986-07-31 WO disclosed
US-4525452-A Enzyme immunoassay with step of immersing sample in deionized water BTC DIAGNOSTICS LIMITED PARTNERSHIP (US) 1985-06-25 US disclosed
US-4503143-A Enzyme immunoassay with two-part solution of tetramethylbenzidine as chromogen BTC DIAGNOSTICS LIMITED PARTNERSHIP (US) 1985-03-05 US disclosed