Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24360027 | 1.00 | MCHR1 (0.55) | MCHR1ADRA2AKMT2AMEN1MAPK1 | |
| SCHEMBL24494392 | 0.94 | MCHR1 (0.52) | MCHR1ADRA2AKMT2AMEN1MAPK1 | |
| SCHEMBL29522167 | 0.91 | GRM5 (0.55) | MCHR1ADRA2AKMT2AMEN1MAPK1 | |
| SCHEMBL25110085 | 0.91 | GRM5 (0.55) | MCHR1ADRA2AKMT2AMEN1MAPK1 | |
| SCHEMBL24494484 | 0.91 | KLK7 (0.53) | MCHR1ADRA2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL29632010 | 0.91 | KLK7 (0.53) | MCHR1ADRA2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL24359952 | 0.91 | KLK7 (0.53) | MCHR1ADRA2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL30540317 | 0.90 | RAB9A (0.55) | MCHR1ADRA2AKMT2AMEN1NPC1 | |
| SCHEMBL24360186 | 0.90 | RAB9A (0.55) | MCHR1ADRA2AKMT2AMEN1NPC1 | |
| SCHEMBL24360359 | 0.90 | GRM5 (0.51) | MCHR1ADRA2AKMT2AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710434-A | Modulators of MAS-related G protein receptor X2 and related products and uses thereof | 伊赛恩特制药公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4232042-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND THEIR USE | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087083-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND THEIR USE | ESCIENT PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |