Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24936291 | 1.00 | KMT2A (0.45) | KMT2AMTNR1AMTNR1BSMN1; SMN2POLB | |
| SCHEMBL24945473 | 0.89 | TNFRSF1A (0.40) | KMT2AMTNR1AMTNR1BSMN1; SMN2POLB | |
| SCHEMBL26608385 | 0.83 | MTNR1A (0.46) | KMT2AMTNR1AMTNR1BSMN1; SMN2POLB | |
| SCHEMBL24977302 | 0.80 | KMT2A (0.52) | KMT2AMTNR1AMTNR1BSMN1; SMN2POLB | |
| SCHEMBL29568731 | 0.79 | CA9 (0.47) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL18865341 | 0.79 | CA9 (0.47) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL24936289 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2POLBNPC1RAB9AMAPK1 | |
| SCHEMBL29632406 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2POLBNPC1RAB9AMAPK1 | |
| SCHEMBL26601614 | 0.76 | POLB (0.49) | KMT2AMTNR1AMTNR1BSMN1; SMN2POLB | |
| SCHEMBL26601891 | 0.75 | NPSR1 (0.43) | KMT2AMTNR1AMTNR1BSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403571-A | Therapeutic agent for cancer having therapeutic resistance to immune checkpoint inhibitor | 住友制药株式会社 | 2025-02-07 | — | — | CN | disclosed |
| WO-2023229032-A1 | THERAPEUTIC FOR CANCER REFRACTORY TO IMMUNE CHECKPOINT INHIBITOR | 住友ファーマ株式会社 | 2023-11-30 | — | — | WO | disclosed |
| CN-116546974-A | 5-heteroaryl-1H-pyrazol-3-amine derivatives | 住友制药株式会社 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022114189-A1 | 5-HETEROARYL-1H-PYRAZOL-3-AMINE DERIVATIVE | 住友ファーマ株式会社 | 2022-06-02 | — | — | WO | disclosed |