SCHEMBL29633103

SCHEMBL29633103

CCOc1c(OC)cc(CCN)cc1SC

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.74
HTR2C P28335 2/20 0.74
HTR2B P41595 2/20 0.74
KDM4E B2RXH2 2/20 0.45
ATM Q13315 1/20 0.45
TAAR1 Q96RJ0 3/20 0.43
TSHR P16473 2/20 0.43
MAPK1 P28482 1/20 0.43
LMNA P02545 3/20 0.42
CYP19A1 P11511 1/20 0.42
GLA P06280 1/20 0.42
AOC3 Q16853 2/20 0.40
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 1/20 0.39
NFKB1 P19838 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20970860 1.00 HTR2A (0.74) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL20970941 0.91 HTR2A (0.59) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL20970865 0.88 HTR2A (0.60) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL29543975 0.88 HTR2A (0.71) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL20970922 0.88 HTR2A (0.71) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL23360647 0.87 HTR2A (0.72) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL29967870 0.87 HTR2A (0.72) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL1119068 0.86 HTR2A (1.00) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL20970970 0.83 HTR2A (0.93) HTR2AHTR2CHTR2BKDM4EATM
SCHEMBL20970881 0.80 HTR2A (0.81) HTR2AHTR2CHTR2BKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same Kuleon, LLC (US) 2025-10-14 US disclosed
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME KULEON LLC (US) 2025-09-11 US disclosed
EP-4452986-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME Kuleon LLC (US) 2024-10-30 EP disclosed
CN-118055766-A Magic and non-magic serotonin receptor agonist and its preparing process and usage 库莱恩有限责任公司 2024-05-17 CN disclosed
WO-2023225043-A1 TRICYCLIC AND TETRACYCLIC SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-11-23 WO disclosed
EP-4251139-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE Wesana Health Inc. (US) 2023-10-04 EP disclosed
EP-4251181-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL CONDITIONS Wesana Health Inc. (US) 2023-10-04 EP disclosed
WO-2023122135-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-06-29 WO disclosed
WO-2023023298-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-23 WO disclosed
WO-2022115798-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE WESANA HEALTH INC. (US) 2022-06-02 WO disclosed
WO-2022115796-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL CONDITIONS WESANA HEALTH INC. (US) 2022-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282722-A1 7-METHYL INDOLE ANALOGS AND DOSAGE FORMS CONTAINING THE SAME HTR7, HTR2C, HTR1A HTR2A 8/4885HTR2C 2/4885HTR2B 7/4885
US-12441683-B2 7-methyl indole analogs and dosage forms containing the same HTR7, HTR2C, HTR1A HTR2A 8/4885HTR2C 2/4885HTR2B 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.