SCHEMBL29633165

SCHEMBL29633165

COc1ccccc1CN

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.69
IDO1 P14902 2/20 0.63
ALDH1A1 P00352 2/20 0.59
GAA P10253 1/20 0.59
MAPT P10636 1/20 0.59
CHRM2 P08172 4/20 0.55
CHRM1 P11229 1/20 0.55
AOC3 Q16853 1/20 0.55
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA9 Q16790 3/20 0.55
CA7 P43166 2/20 0.55
CA12 O43570 2/20 0.55
CA14 Q9ULX7 2/20 0.55
CA4 P22748 1/20 0.55
LMNA P02545 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
SIGMAR1 Q99720 1/20 0.50
ADRA2B P18089 1/20 0.50
PTGS1 P23219 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39970 1.00 TAAR1 (0.69) TAAR1IDO1ALDH1A1GAAMAPT
Hydrochloric Acid SCHEMBL9272901 0.98 TAAR1 (0.67) TAAR1IDO1ALDH1A1GAAMAPT
Hydrochloric Acid SCHEMBL27527127 0.98 TAAR1 (0.67) TAAR1IDO1ALDH1A1GAAMAPT
Ammonia Solution, Strong SCHEMBL7689341 0.98 TAAR1 (0.67) TAAR1IDO1ALDH1A1GAAMAPT
SCHEMBL2782786 0.90 TAAR1 (0.58) TAAR1IDO1ALDH1A1GAAMAPT
Toluene SCHEMBL28863023 0.90 TAAR1 (0.58) TAAR1IDO1ALDH1A1GAAMAPT
Aniline SCHEMBL22169202 0.90 TAAR1 (0.58) TAAR1IDO1ALDH1A1GAAMAPT
Acetonitrile SCHEMBL3928449 0.90 TAAR1 (0.58) TAAR1IDO1ALDH1A1GAAMAPT
SCHEMBL8356887 0.88 TAAR1 (0.56) TAAR1IDO1ALDH1A1GAAMAPT
SCHEMBL3866915 0.88 TAAR1 (0.61) TAAR1IDO1ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735441-A1 PYRROLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF MENTAL ILLNESSES Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 EP disclosed
EP-3820860-B1 PYRIDAZINE COMPOUNDS FOR INHIBITING NAV1.8 LIEBER INST INC (US) 2025-10-15 EP disclosed
US-20250145472-A1 METHOD FOR GENERATING CARBON DIOXIDE KOBE GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-05-08 US disclosed
EP-4139286-B1 SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION BAYER AG (DE) 2025-02-26 EP disclosed
WO-2025021943-A1 QUINAZOLINONE, BENZOXAZINONE AND BENZOXAZEPINONE DERIVATIVES AS PROTEIN KINASE INHIBITORS NEURALIS (BE) 2025-01-30 WO disclosed
WO-2025000051-A1 PYRROLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF MENTAL ILLNESSES Psylo Pty Ltd (AU) 2025-01-02 WO disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed
EP-4480568-A1 METHOD FOR GENERATING CARBON DIOXIDE Kobe Gakuin Educational Foundation (JP) 2024-12-25 EP disclosed
US-11964953-B2 Substituted aminothiazoles as DGKzeta inhibitors for immune activation BAYER AKTIENGESELLSCHAFT (DE) 2024-04-23 US disclosed
WO-2023153506-A1 METHOD FOR GENERATING CARBON DIOXIDE 学校法人神戸学院 2023-08-17 WO disclosed
WO-2023150374-A1 INDUCERS OF KLF2 AND METHODS OF USE THEREOF RIPARIAN PHARMACEUTICALS, INC. (US) 2023-08-10 WO disclosed
US-20230167078-A1 SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION BAYER AKTIENGESELLSCHAFT (DE) 2023-06-01 US disclosed
CN-116194440-A Quinazolinone HSD17B13 inhibitors and uses thereof 伊尼制药公司 2023-05-30 CN disclosed
US-20230139936-A1 SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION BAYER AKTIENGESELLSCHAFT (DE) 2023-05-04 US disclosed
US-11530226-B2 Azepane inhibitors of menin-MLL interaction JANSSEN PHARMACEUTICA NV (BE) 2022-12-20 US disclosed
CN-115443277-A Compounds as kinase inhibitors 重庆复尚源创医药技术有限公司 2022-12-06 CN disclosed
CN-114716381-A Compounds useful as kinase inhibitors 洛克索肿瘤学股份有限公司 2022-07-08 CN disclosed
EP-4010330-A1 QUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS B.C.I. Pharma (BE) 2022-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230139936-A1 SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION DGKZ, DGKA, DGKG TAAR1 3075/4885IDO1 1682/4885ALDH1A1 3985/4885
US-20230167078-A1 SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION DGKZ, DGKA, DGKG TAAR1 3075/4885IDO1 1682/4885ALDH1A1 3985/4885
US-11964953-B2 Substituted aminothiazoles as DGKzeta inhibitors for immune activation DGKZ, DGKA, DGKG TAAR1 3075/4885IDO1 1682/4885ALDH1A1 3985/4885
US-11530226-B2 Azepane inhibitors of menin-MLL interaction MEN1, MLLT1, BMI1 TAAR1 4450/4885IDO1 2136/4885ALDH1A1 3880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.