Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.77 |
| ▸ | HTT | P42858 | 6/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 6/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | BLM | P54132 | 5/20 | 0.77 |
| ▸ | CASP3 | P42574 | 4/20 | 0.77 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.77 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.77 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | TDP2 | O95551 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 2/20 | 0.77 |
| ▸ | NSD2 | O96028 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 7/20 | 0.75 |
| ▸ | NPC1 | O15118 | 6/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14571425 | 1.00 | MAPT (0.77) | MAPTMAPK1HTTL3MBTL1LMNA | |
| SCHEMBL5541831 | 0.87 | MAPT (1.00) | MAPTMAPK1HTTL3MBTL1LMNA | |
| SCHEMBL31654022 | 0.87 | MAPT (1.00) | MAPTMAPK1HTTL3MBTL1LMNA | |
| SCHEMBL7912631 | 0.86 | MAPT (0.80) | MAPTMAPK1HTTL3MBTL1LMNA | |
| SCHEMBL754259 | 0.86 | MAPT (1.00) | MAPTMAPK1HTTL3MBTL1LMNA | |
| SCHEMBL29633257 | 0.86 | MAPT (1.00) | MAPTMAPK1HTTL3MBTL1LMNA | |
| SCHEMBL14441061 | 0.85 | MAPT (0.56) | MAPTMAPK1HTTL3MBTL1LMNA | |
| SCHEMBL14441059 | 0.85 | MAPT (0.60) | MAPTMAPK1HTTL3MBTL1LMNA | |
| SCHEMBL28408126 | 0.84 | MAPT (0.96) | MAPTMAPK1HTTL3MBTL1LMNA | |
| SCHEMBL30991487 | 0.84 | MAPT (0.71) | MAPTMAPK1HTTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271193-A | Method for promoting catalytic synthesis of 2-amino-1, 4-naphthoquinone compounds by using nicotinic acid as ligand and using dichloro-titanocene | 宁夏师范学院 | 2024-07-02 | — | — | CN | disclosed |
| CN-114702399-A | 2-trifluoroalkyl-1, 4-naphthoquinone compound and synthetic method thereof | 信阳师范学院 | 2022-07-05 | — | — | CN | disclosed |
| CN-109748809-B | Method for synthesizing 2-substituted amino-1, 4-naphthoquinone derivative | 中国科学院成都有机化学有限公司 | 2022-05-13 | — | — | CN | disclosed |