Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546147 | 1.00 | METAP1 (0.57) | METAP1ACHEHTR2AHTR2CADORA1 | |
| SCHEMBL22738419 | 0.95 | METAP1 (0.53) | METAP1ACHEHTR2AHTR2CADORA1 | |
| SCHEMBL21694418 | 0.93 | METAP1 (0.52) | METAP1ACHEHTR2AHTR2CADORA1 | |
| SCHEMBL547186 | 0.89 | ALDH1A1 (0.53) | METAP1ACHEHTR2CCYP1A2MAOA | |
| SCHEMBL22079199 | 0.87 | CHEK2 (0.47) | METAP1ACHEHTR2AHTR2CADORA1 | |
| SCHEMBL12704854 | 0.87 | ESR1 (0.47) | METAP1ACHEHTR2AHTR2CADORA1 | |
| SCHEMBL1609651 | 0.85 | METAP1 (0.71) | METAP1ACHEHTR2AHTR2CADORA1 | |
| SCHEMBL10357662 | 0.85 | METAP1 (0.46) | METAP1ACHEHTR2AHTR2CADORA1 | |
| SCHEMBL29332473 | 0.84 | METAP1 (0.53) | METAP1ACHEHTR2AHTR2CPARP1 | |
| SCHEMBL6056920 | 0.84 | METAP1 (0.69) | METAP1ACHEHTR2AHTR2CADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756967-A | Silicon bridged metallocene catalyst and application thereof | 上海化工研究院有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117603275-A | Preparation method of polyketone catalyst and application of polyketone catalyst in catalyzing polyketone synthesis | 万华化学集团股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-113443950-B | Method for reducing carbonyl into methylene under illumination | 中山大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-109824809-B | Ethylene-alpha-olefin-nonconjugated polyene copolymer and use thereof | 三井化学株式会社 | 2022-06-28 | — | — | CN | disclosed |