SCHEMBL546147

SCHEMBL546147

Cc1ccc2c(c1)-c1cc(C)ccc1C2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 3/20 0.57
ACHE P22303 3/20 0.47
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
ADORA1 P30542 1/20 0.46
PARP1 P09874 1/20 0.45
PARP10 Q53GL7 1/20 0.45
CYP19A1 P11511 2/20 0.43
CYP11B2 P19099 2/20 0.43
CYP1A2 P05177 2/20 0.41
CYP2A6 P11509 2/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
MAPT P10636 3/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633503 1.00 METAP1 (0.57) METAP1ACHEHTR2AHTR2CADORA1
SCHEMBL22738419 0.95 METAP1 (0.53) METAP1ACHEHTR2AHTR2CADORA1
SCHEMBL21694418 0.93 METAP1 (0.52) METAP1ACHEHTR2AHTR2CADORA1
SCHEMBL547186 0.89 ALDH1A1 (0.53) METAP1ACHEHTR2CCYP1A2MAOA
SCHEMBL22079199 0.87 CHEK2 (0.47) METAP1ACHEHTR2AHTR2CADORA1
SCHEMBL12704854 0.87 ESR1 (0.47) METAP1ACHEHTR2AHTR2CADORA1
SCHEMBL1609651 0.85 METAP1 (0.71) METAP1ACHEHTR2AHTR2CADORA1
SCHEMBL10357662 0.85 METAP1 (0.46) METAP1ACHEHTR2AHTR2CADORA1
SCHEMBL29332473 0.84 METAP1 (0.53) METAP1ACHEHTR2AHTR2CPARP1
SCHEMBL6056920 0.84 METAP1 (0.69) METAP1ACHEHTR2AHTR2CADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092028-A1 ONE-POT SYNTHESIS OF SUBSTITUTED FLOURENES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-04-02 US disclosed
CN-117756967-A Silicon bridged metallocene catalyst and application thereof 上海化工研究院有限公司 2024-03-26 CN disclosed
CN-113443950-B Method for reducing carbonyl into methylene under illumination 中山大学 2023-11-03 CN disclosed
US-11760819-B2 Ethylene α-olefin non-conjugated polyene copolymer, use thereof, and manufacturing method thereof MITSUI CHEMICALS, INC. (JP) 2023-09-19 US disclosed
US-11613595-B2 Ethylene alpha-olefin non-conjugated polyene copolymer, use thereof, and manufacturing method thereof MITSUI CHEMICALS, INC. (JP) 2023-03-28 US disclosed
EP-4043500-A1 ETHYLENE·ALPHA-OLEFIN·NON-CONJUGATED POLYENE COPOLYMER, USE THEREOF, AND MANUFACTURING METHOD THEREOF Mitsui Chemicals, Inc. (JP) 2022-08-17 EP disclosed
CN-109824809-B Ethylene-alpha-olefin-nonconjugated polyene copolymer and use thereof 三井化学株式会社 2022-06-28 CN disclosed
EP-3106480-B1 ETHYLENE/A-OLEFIN/NON-CONJUGATED POLYENE COPOLYMER, USE THEREFOR, AND MANUFACTURING METHOD THEREFOR MITSUI CHEMICALS INC (JP) 2022-04-06 EP disclosed
CN-113443950-A Method for reducing carbonyl into methylene under illumination 中山大学 2021-09-28 CN disclosed
US-20210122860-A1 ETHYLENE ALPHA-OLEFIN NON-CONJUGATED POLYENE COPOLYMER, USE THEREOF, AND MANUFACTURING METHOD THEREOF MITSUI CHEMICALS, INC. (JP) 2021-04-29 US disclosed
US-20170283546-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-05 US disclosed
EP-3106480-A1 ETHYLENE/A-OLEFIN/NON-CONJUGATED POLYENE COPOLYMER, USE THEREFOR, AND MANUFACTURING METHOD THEREFOR Mitsui Chemicals, Inc. (JP) 2016-12-21 EP disclosed
US-20160347894-A1 ETHYLENE ALPHA-OLEFIN NON-CONJUGATED POLYENE COPOLYMER, USE THEREOF, AND MANUFACTURING METHOD THEREOF MITSUI CHEMICALS, INC. (JP) 2016-12-01 US disclosed
WO-2016180511-A1 METAL COMPLEXES AND ELECTROLUMINESCENT DEVICES COMPRISING THESE METAL COMPLEXES MERCK PATENT GMBH (DE) 2016-11-17 WO disclosed
US-8299459-B2 Diindenopicene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2012-10-30 US disclosed
CN-101107260-B Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer SUMITOMO CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
US-8110294-B2 Fluorene compound; steric hindrance CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed
US-8084559-B2 Ethylene-vinylcyclohexane copolymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-27 US disclosed
US-20080200736-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-08-21 US disclosed
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200736-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME LEF1, FMNL1, AFF1 METAP1 1845/4885ACHE 3105/4885HTR2A 2672/4885
US-20080161514-A1 Transition Metal Complex, Process For Producing Said Transition Metal Complex, Substituent-Carrying Fluorene Compound, Process For Producing Said Fluorene Compound, Catalyst Component For Olefin Polymerization, Catalyst For Olefin Polymerization, and Process For Producing Olefin Polymer AOC2, ACSL1, ACSL3 METAP1 2844/4885ACHE 3763/4885HTR2A 4366/4885
US-20260092028-A1 ONE-POT SYNTHESIS OF SUBSTITUTED FLOURENES DYRK1B, DYRK2, DYRK4 METAP1 2580/4885ACHE 3189/4885HTR2A 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.