Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28715365 | 0.82 | ALDH1A1 (0.38) | HTTLMNATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL24488936 | 0.73 | HTT (0.37) | HTTLMNATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL22946263 | 0.73 | LMNA (0.57) | HTTLMNATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL29633557 | 0.73 | TSHR (0.44) | HTTLMNATHRBALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL28715398 | 0.72 | POLB (0.36) | HTTLMNAALDH1A1SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL28715397 | 0.72 | POLB (0.36) | HTTLMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL22946248 | 0.71 | HTR2A (0.36) | HTTLMNATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL358283 | 0.70 | LMNA (0.45) | HTTLMNATHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL14094901 | 0.68 | MAPT (0.39) | HTTLMNAALDH1A1TSHRCYP1A2 | |
| SCHEMBL670340 | 0.68 | TSHR (0.41) | HTTLMNATHRBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |