Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24371395 | 0.86 | TSHR (0.49) | TSHRCYP3A4CREBBPCA9HSD17B10 | |
| SCHEMBL22946243 | 0.78 | BCHE (0.45) | TSHRCYP3A4CREBBPCA9SMN1; SMN2 | |
| SCHEMBL22945780 | 0.77 | CYP3A4 (0.41) | TSHRCYP3A4CREBBPCA9SMN1; SMN2 | |
| SCHEMBL22946254 | 0.77 | TSHR (0.42) | TSHRCYP3A4CREBBPCA9HSD17B10 | |
| SCHEMBL22945777 | 0.77 | CREBBP (0.54) | TSHRCYP3A4CREBBPCA9HSD17B10 | |
| SCHEMBL22946040 | 0.77 | TSHR (0.53) | TSHRCYP3A4CREBBPCA9HSD17B10 | |
| SCHEMBL24489022 | 0.77 | ALDH1A1 (0.37) | TSHRHSD17B10SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL22945769 | 0.77 | ALDH1A1 (0.37) | TSHRHSD17B10SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL24488957 | 0.76 | LMNA (0.43) | TSHRCYP3A4CREBBPCA9RORC | |
| SCHEMBL22945672 | 0.76 | LMNA (0.43) | TSHRCYP3A4CREBBPCA9RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |