Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154252 | 0.81 | ALDH1A1 (0.32) | ALDH1A1THRBKMT2ACA1CA2 | |
| SCHEMBL7695741 | 0.77 | HDAC8 (0.48) | HDAC8HDAC6ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7180667 | 0.76 | HDAC8 (0.52) | HDAC8HDAC6LMNASMN1; SMN2NPSR1 | |
| SCHEMBL19060 | 0.75 | HDAC8 (0.52) | HDAC8HDAC6ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11031178 | 0.74 | HDAC8 (0.56) | HDAC8HDAC6ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11139466 | 0.74 | HDAC8 (0.56) | HDAC8HDAC6ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15082184 | 0.72 | HDAC8 (0.48) | HDAC8HDAC6ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL15931748 | 0.72 | HDAC8 (0.43) | HDAC8HDAC6ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22169725 | 0.69 | HDAC8 (0.50) | HDAC8HDAC6ALDH1A1LMNAHTT | |
| SCHEMBL27657081 | 0.68 | TSHR (0.46) | HDAC8HDAC6ALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |