Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634962 | 0.84 | TDP1 (0.48) | TDP1TSHRCYP3A4ALDH1A1HTT | |
| SCHEMBL28706149 | 0.84 | TDP1 (0.48) | TDP1TSHRCYP3A4ALDH1A1HTT | |
| SCHEMBL28719326 | 0.80 | TDP1 (0.45) | TDP1TSHRCYP3A4ALDH1A1HTT | |
| SCHEMBL31634964 | 0.80 | TDP1 (0.45) | TDP1TSHRCYP3A4ALDH1A1HTT | |
| SCHEMBL4264560 | 0.80 | KDM4E (0.50) | TDP1CYP3A4ALDH1A1HTTKMT2A | |
| SCHEMBL11928957 | 0.73 | TDP1 (0.49) | TDP1TSHRCYP3A4ALDH1A1HTT | |
| SCHEMBL5657695 | 0.73 | KDM4E (0.61) | ALDH1A1SMN1; SMN2LMNAGAAHSD17B10 | |
| SCHEMBL21828904 | 0.72 | HCRTR1 (0.48) | TDP1TSHRALDH1A1HTTKMT2A | |
| SCHEMBL28410942 | 0.71 | ALDH1A1 (0.59) | TDP1TSHRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4304698 | 0.71 | TSHR (0.47) | TDP1TSHRCYP3A4ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |