Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31634962 | 1.00 | TDP1 (0.48) | TDP1TSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL31634964 | 0.86 | TDP1 (0.45) | TDP1TSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL28719326 | 0.86 | TDP1 (0.45) | TDP1TSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL29633584 | 0.84 | TDP1 (0.43) | TDP1TSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL11928957 | 0.79 | TDP1 (0.49) | TDP1TSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL28126602 | 0.78 | TDP1 (0.48) | TDP1TSHRALDH1A1KMT2AHTT | |
| SCHEMBL23125524 | 0.77 | TDP1 (0.39) | TDP1ALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL16575395 | 0.76 | TSHR (0.44) | TSHRCYP3A4ALDH1A1KMT2AHTT | |
| SCHEMBL4304698 | 0.76 | TSHR (0.47) | TDP1TSHRCYP3A4ALDH1A1KMT2A | |
| SCHEMBL29633582 | 0.76 | KDM4E (0.51) | TDP1TSHRALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823001-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-114206832-B | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2025-04-04 | — | — | CN | disclosed |
| CN-114206832-A | Urea compounds antagonizing LPA1 receptor | 大正制药株式会社 | 2022-03-18 | — | — | CN | disclosed |