Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24435785 | 1.00 | ERN1 (0.52) | ERN1MAPK10 | |
| SCHEMBL24435821 | 1.00 | ERN1 (0.52) | ERN1MAPK10 | |
| SCHEMBL24435930 | 0.93 | ERN1 (0.54) | ERN1MAPK10 | |
| SCHEMBL29633594 | 0.93 | ERN1 (0.54) | ERN1MAPK10 | |
| SCHEMBL24435789 | 0.92 | ERN1 (0.53) | ERN1MAPK10 | |
| SCHEMBL24439288 | 0.85 | ERN1 (0.47) | ERN1MAPK10 | |
| SCHEMBL24435877 | 0.84 | ERN1 (0.43) | ERN1MAPK10 | |
| SCHEMBL24435934 | 0.81 | ERN1 (0.51) | ERN1MAPK10 | |
| SCHEMBL29633651 | 0.81 | ERN1 (0.51) | ERN1MAPK10 | |
| SCHEMBL25072021 | 0.81 | ERN1 (0.69) | ERN1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4243815-A1 | IRE1ALPHA INHIBITORS AND USES THEREOF | The Regents of the University of California (US) | 2023-09-20 | — | — | EP | disclosed |
| WO-2022104151-A1 | IRE1ALPHA INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-19 | — | — | WO | disclosed |