SCHEMBL29633641

SCHEMBL29633641

CN(C(=O)OCC1c2ccccc2-c2ccccc21)C(Cc1ccccn1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPRA P18433 1/20 0.42
FABP5 Q01469 3/20 0.38
FABP7 O15540 2/20 0.38
KMT2A Q03164 2/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
MDM4 O15151 2/20 0.37
TP53 P04637 2/20 0.37
CASP3 P42574 1/20 0.36
MAOB P27338 1/20 0.36
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
PPARG P37231 1/20 0.35
PPARA Q07869 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25358797 0.91 HDAC1 (0.38) PTPRAFABP5FABP7KMT2AHDAC1
SCHEMBL25358794 0.91 HDAC1 (0.38) PTPRAFABP5FABP7KMT2AHDAC1
SCHEMBL31370332 0.89 FABP5 (0.40) FABP5FABP7KMT2AHDAC1HDAC2
SCHEMBL16289467 0.85 FABP5 (0.37) FABP5FABP7KMT2AMDM4TP53
SCHEMBL30510336 0.85 FABP5 (0.37) FABP5FABP7KMT2AMDM4TP53
SCHEMBL15083320 0.85 FABP5 (0.37) FABP5FABP7KMT2AMDM4TP53
SCHEMBL25358159 0.85 FABP5 (0.36) FABP5FABP7KMT2AMDM4TP53
SCHEMBL25358152 0.85 FABP5 (0.36) FABP5FABP7KMT2AMDM4TP53
SCHEMBL28737117 0.85 KMT2A (0.37) FABP5FABP7KMT2AMDM4TP53
Hydrochloric Acid SCHEMBL31689016 0.85 FABP5 (0.36) FABP5FABP7KMT2AMDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US disclosed
US-12071396-B2 Method for preparing aromatic amino acid derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-27 US disclosed
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR PTPRA 1915/4885FABP5 608/4885FABP7 1148/4885
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR PTPRA 1915/4885FABP5 608/4885FABP7 1148/4885
US-12071396-B2 Method for preparing aromatic amino acid derivative DDC, AADAT, TYR PTPRA 1915/4885FABP5 608/4885FABP7 1148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.