SCHEMBL29633800

SCHEMBL29633800

COc1ccccc1CCC(C(=O)O)N(C)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 5/20 0.47
FABP7 O15540 4/20 0.41
FABP3 P05413 2/20 0.41
KMT2A Q03164 4/20 0.38
MEN1 O00255 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
EPHX2 P34913 1/20 0.36
MDM2 Q00987 1/20 0.36
AOC3 Q16853 1/20 0.36
PTGFR P43088 1/20 0.36
GAA P10253 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
CASP3 P42574 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31370225 1.00 FABP5 (0.47) FABP5FABP7FABP3KMT2AMEN1
SCHEMBL31688691 0.92 FABP5 (0.45) FABP5FABP7FABP3KMT2AMEN1
SCHEMBL30802525 0.90 FABP5 (0.49) FABP5FABP7FABP3KMT2AMEN1
SCHEMBL29855074 0.90 FABP5 (0.49) FABP5FABP7FABP3KMT2AMEN1
SCHEMBL25179576 0.90 FABP5 (0.49) FABP5FABP7FABP3KMT2AMEN1
SCHEMBL25178777 0.90 FABP5 (0.49) FABP5FABP7FABP3KMT2AMEN1
SCHEMBL31688678 0.89 FABP5 (0.42) FABP5KMT2AMEN1MDM2TDP1
SCHEMBL29633916 0.88 FABP5 (0.42) FABP5FABP7FABP3KMT2AMEN1
SCHEMBL31369666 0.88 FABP5 (0.44) FABP5KMT2AALDH1A1
SCHEMBL29633873 0.88 FABP5 (0.44) FABP5KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US disclosed
US-12071396-B2 Method for preparing aromatic amino acid derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-27 US disclosed
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR FABP5 608/4885FABP7 1148/4885FABP3 1794/4885
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR FABP5 608/4885FABP7 1148/4885FABP3 1794/4885
US-12071396-B2 Method for preparing aromatic amino acid derivative DDC, AADAT, TYR FABP5 608/4885FABP7 1148/4885FABP3 1794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.