SCHEMBL29633898

SCHEMBL29633898

CNC(=O)c1cc(CCC(C(=O)OC(C)(C)C)N(C)C(=O)OCC2c3ccccc3-c3ccccc32)ccc1OC

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 1/20 0.35
PPARA Q07869 7/20 0.34
PPARG P37231 4/20 0.34
KMT2A Q03164 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ITGA4 P13612 1/20 0.33
ITGB7 P26010 1/20 0.33
EPHX2 P34913 1/20 0.33
GAA P10253 1/20 0.33
PKM P14618 1/20 0.33
AAK1 Q2M2I8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633945 0.94 FABP5 (0.35) FABP5KMT2AADRB2ADRB1ADRB3
SCHEMBL29633713 0.92 PPARA (0.38) FABP5PPARAPPARG
SCHEMBL29633858 0.90 PPARA (0.40) FABP5PPARAPPARGKMT2A
SCHEMBL29633852 0.90 FABP5 (0.39) FABP5KMT2AADRB2ADRB1ADRB3
SCHEMBL29633688 0.87 CHRM5 (0.38) FABP5ADRB2ADRB1ADRB3
SCHEMBL29633974 0.86 FABP5 (0.36) FABP5PPARAKMT2AITGA4ITGB7
SCHEMBL22091955 0.84 FABP5 (0.39) FABP5PPARAPPARGKMT2AEPHX2
SCHEMBL22091956 0.84 FABP5 (0.39) FABP5PPARAPPARGKMT2AEPHX2
SCHEMBL28741578 0.84 PTPN1 (0.41)
SCHEMBL29633842 0.83 PPARA (0.44) FABP5PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI PHARMACEUTICAL CO LTD (JP) 2024-11-14 US disclosed
US-12071396-B2 Method for preparing aromatic amino acid derivative CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-08-27 US disclosed
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376044-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR FABP5 608/4885PPARA 658/4885PPARG 1123/4885
US-20220144762-A1 METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE DDC, AADAT, TYR FABP5 608/4885PPARA 658/4885PPARG 1123/4885
US-12071396-B2 Method for preparing aromatic amino acid derivative DDC, AADAT, TYR FABP5 608/4885PPARA 658/4885PPARG 1123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.