Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633932 | 0.94 | ITGB1 (0.33) | ITGB1ITGA4FABP5HPGDCACNA1B | |
| SCHEMBL29633879 | 0.92 | ITGB1 (0.39) | ITGB1ITGA4FABP5HPGDCTSD | |
| SCHEMBL29633856 | 0.86 | ITGB1 (0.40) | ITGB1ITGA4CACNA1B | |
| SCHEMBL29633974 | 0.85 | FABP5 (0.36) | ITGA4FABP5HPGD | |
| SCHEMBL29633859 | 0.82 | CACNA1B (0.37) | ITGB1ITGA4CACNA1B | |
| SCHEMBL30278708 | 0.81 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL22108651 | 0.81 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL22108650 | 0.81 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL22108653 | 0.81 | ITGB1 (0.48) | ITGB1ITGA4 | |
| SCHEMBL22108655 | 0.81 | ITGB1 (0.48) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376044-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2024-11-14 | — | — | US | disclosed |
| US-12071396-B2 | Method for preparing aromatic amino acid derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-08-27 | — | — | US | disclosed |
| US-20220144762-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376044-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | DDC, AADAT, TYR | ITGB1 4860/4885ITGA4 4597/4885FABP5 608/4885 |
| US-20220144762-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | DDC, AADAT, TYR | ITGB1 4860/4885ITGA4 4597/4885FABP5 608/4885 |
| US-12071396-B2 | Method for preparing aromatic amino acid derivative | DDC, AADAT, TYR | ITGB1 4860/4885ITGA4 4597/4885FABP5 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.